We are seeking a highly motivated Post-doctoral Researcher in Medicinal Chemistry to join our dynamic team at Université Cote d’Azur’s Institut de Chimie de Nice, in collaboration with Sanofi. This project focuses on the development of novel RNA ligands for therapeutic applications, utilizing innovative strategies such as RIBOTAC and covalent modification of RNA targets.
SCHOLARSHIP AT A GLANCE:
| Position | Post-doctoral Researcher in Medicinal Chemistry |
|---|---|
| Institution | Université Cote d’Azur’s Institut de Chimie de Nice |
| Collaboration | Sanofi |
| Project Focus | Development of novel RNA ligands for therapeutic applications |
| Strategies Used | RIBOTAC, Covalent RNA modification |
| Evaluation Methods | In vitro and cellular assessment for affinity, selectivity, and activity |
| Outcome | Design and synthesis of optimized compounds for therapeutic use |
| Eligibility | – PhD in Organic Chemistry, Medicinal Chemistry, or Chemical Biology (within last 2 years) |
| – Strong knowledge and experience in organic chemistry | |
| – High motivation and interest in chemistry-biology interface projects | |
| Required Documents | – CV (including contacts of at least two previous supervisors) |
| – Cover letter (describing scientific interests and career plans) | |
| Application Language | English or French |
| Application Contact | Dr. Maria Duca (maria.duca@univ-cotedazur.fr) |
| Application Deadline | End of September 2024 |
| Position Start Date | Flexible, between October 2024 and January 2025 |
Facts About Université Cote d’Azur
- Top-Tier Research Hub: Université Cote d’Azur’s Institut de Chimie de Nice is renowned for cutting-edge research, making groundbreaking strides in medicinal chemistry and chemical biology.
- Innovative Collaborations: Partnered with global pharmaceutical giant Sanofi, the university is at the forefront of developing revolutionary RNA-based therapeutics, setting new standards in the industry.
- Pioneering Projects: The university is a leader in utilizing advanced strategies like RIBOTAC and covalent RNA modification, pushing the boundaries of what’s possible in drug discovery and development.
- State-of-the-Art Facilities: Equipped with world-class laboratories and research facilities, Université Cote d’Azur provides an unparalleled environment for scientific innovation and discovery.
- Global Impact: Research from the university’s Institut de Chimie de Nice has significant implications, contributing to global health advancements and positioning itself as a beacon of excellence in scientific research.
- Elite Academic Team: The university boasts a dynamic team of highly motivated and accomplished researchers, driving forward the next generation of therapeutic solutions with passion and expertise.
- Prestigious Location: Situated in the beautiful and bustling city of Nice, the university offers a vibrant cultural experience alongside academic excellence, attracting top talent from around the world.
- Remarkable Success Stories: Université Cote d’Azur has a history of producing influential research outcomes and successful alumni who continue to make significant contributions in their respective fields globally.
Eligibility For 2024 Scholarship in Medicinal Chemistry, ICN
- PhD in Organic Chemistry, Medicinal Chemistry, or Chemical Biology obtained within the last 2 years.
- Strong knowledge and experience in organic chemistry.
- High motivation and interest in projects at the chemistry-biology interface.
Description For 2024 Scholarship in Medicinal Chemistry, ICN
- Project Focus: RNA represents a promising therapeutic target for innovative drug discovery. This project aims to develop novel RNA ligands with properties that enable RNA degradation or covalent modification.
- Approach: Utilize strategies like RIBOTAC (similar to PROTACS) and introduce chemical motifs for covalent RNA binding.
- Evaluation: Assess the bioactive molecules for affinity, selectivity, and activity on various RNA targets in vitro and at the cellular level through biological collaborations.
- Outcome: Design and synthesize optimized compounds for potential therapeutic applications.
How to Apply For 2024 Scholarship in Medicinal Chemistry, ICN
Interested candidates should send the following documents:
- CV (including contacts of at least two previous supervisors)
- Cover letter (describing scientific interests and career plans)
Send applications in English or French to Dr. Maria Duca at maria.duca@univ-cotedazur.fr.
Last Date for Application:
Please apply by the end of September 2024. The start date for the position is flexible, between October 2024 and January 2025.